Details for amaxa FAQ article #353

«What kind of effects could a mycoplasma contamination have on my cells?»

Mycoplasma contamination can:
> Inhibit cell metabolism
> Cause cell death
> Induce morphological alterations
> Alter DNA, RNA, and protein synthesis
> Induce chromosomal aberrations
> Cause increased sensitivity to inducers of apoptosis
> Change membrane antigenicity
> Alter transfection efficiency
> Compromise viral production